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Pre-clinical validation of medical devices, pharmaceuticals, and regenerative medicine using porcine large animal models.
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Contains surgical imagery
Neuro/Sensory Models
Retinal prosthesis, neurostimulation, cochlear implants, and ophthalmic surgery
Contains surgical imagery
Stem Cell/Regenerative Models
Neural regeneration, tissue engineering, and allotransplantation
Contains surgical imagery
Spine/Orthopedic Models
Spinal fusion, bone screws, ligament reconstruction, and cartilage repair
Contains surgical imagery
Organ Models
Liver, lung, intestine, bladder, transplantation, and laparoscopic research
Contains surgical imagery
Pharmacological Models
Pharmacokinetics, formulation development, and safety evaluation
Service Models
Neuro/Sensory Models
Our neuro/sensory models support neuromodulation, electronic retinal implantation, cochlear implant systems, and brain research. The porcine nervous system provides an ideal testing platform for neurostimulation devices and sensory implants.
Experiment Types
- Parkinson's disease animal model establishment
- Minimally invasive neurostimulation modulator development
- Wireless transcranial and deep brain stimulation verification
- Bone-conduction cochlear implant system animal validation
- Ultra-high frequency neurostimulator implant safety evaluation
- Implant electrode material long-term biocompatibility observation
- Electronic retinal chip implantation and visual evoked potential testing
- Ophthalmic laser surgery research
Associated Clients
- ACE Vision Group
- Taipei Medical University
- Hualien Tzu Chi Hospital
- China Medical University Hospital
- Industrial Technology Research Institute
- National Yang Ming Chiao Tung University
Stem Cell/Regenerative Models
Our stem cell/regenerative models support regenerative medicine research, including neural regeneration therapy, cartilage tissue engineering, xenogeneic and allogeneic tissue transplantation, and pre-clinical stem cell therapy evaluation. The porcine model offers an excellent platform for translational regenerative medicine.
Experiment Types
- Stem cell pre-clinical eval
- Neural regeneration therapy
- Cartilage tissue engineering
- Composite tissue allotransplant
- Xenogeneic tissue reconstruction
Associated Clients
- Taipei Medical University
- National Defense Medical Center
- National Health Research Institutes
- China Medical University Hospital
- Industrial Technology Research Institute
Spine/Orthopedic Models
The porcine spine and skeletal system closely mimic human biomechanical properties. Our spine/orthopedic models encompass spinal fusion devices, vertebral body supports, bone screw systems, ligament reconstruction, and cartilage repair — our most experienced research area.
Experiment Types
- Biodegradable orthopedic implants
- Disc repair and spinal correction
- Bone screw fixation system development
- Articular cartilage repair and regeneration
- Spinal fusion device development and validation
Associated Clients
- Wiltrom Co., Ltd.
- Fu Jen Catholic University
- Taipei Medical University
- BioGend Therapeutics Co., Ltd.
- National Taiwan University Hospital
Organ Models
We provide specialized organ system models covering laparoscopic surgical instrument testing, organ transplantation research, gastrointestinal endoscopic surgery, and urological evaluation. Porcine organs closely match human counterparts in size and function.
Experiment Types
- GI surgical device evaluation
- Laparoscopic instrument testing
- Pulmonary photodynamic therapy
- Urological & ostomy device eval
- Organ transplant preclinical study
Associated Clients
- Medeon Biodesign Inc.
- Taiwan Liposome Company
- A Prevent Medical Inc.
- MOHW Taoyuan General Hospital
- China Medical University Hospital
Related Articles
- From One Pig Heart to 69 Gene Edits: Four Years of Xenotransplantation Progress
From the first living human heart transplant in 2022 to formal FDA-regulated clinical trials by 2025, xenotransplantation has moved from a one-off case to a defined technical pathway in just four years.
Pharmacological Models
Our pharmacological models support diverse pre-clinical drug development needs, including oral and injectable formulation pharmacokinetics, local irritation assessment, bioavailability analysis, and traditional herbal medicine metabolism studies.
Experiment Types
- Drug local irritation and safety testing
- Immunogenicity testing and vaccine development
- Enteric-coated capsule gastrointestinal studies
- Nanoparticle drug infusion reaction pharmacology
- Traditional Chinese medicine metabolomics analysis
- Oral and injectable formulation pharmacokinetic studies
- Subcutaneous injection drug distribution characterization
Associated Clients
- TTY Biopharm Co., Ltd.
- Alar Pharmaceuticals Inc.
- Rosetta Biotech Consulting
- National Health Research Institutes
- Development Center for Biotechnology
Cardiovascular Models
Our cardiovascular porcine models support a wide range of cardiac and vascular research. The pig cardiovascular system closely resembles human anatomy, making it an ideal platform for vascular stents, artificial vessels, vascular closure devices, and cardiac pacemaker pre-clinical testing.
Experiment Types
- Arteriovenous fistula efficacy assessment
- Artificial vessel safety and efficacy evaluation
- Leadless cardiac pacemaker implantation training
- Bioresorbable vascular scaffold technology development
- Vascular closure device pre-clinical feasibility testing
- Ultrasonic thrombolysis device animal model validation
- Biodegradable vascular stent implantation and functional validation
Associated Clients
- Abbott Taiwan
- SGH Biotech Co., Ltd.
- Medeon Biodesign Inc.
- National Tsing Hua University
- National Taiwan University of Science and Technology
Related Articles
- A Pig's Heart, a Human's Catheter: The Science of Cardiovascular Device Testing
A pig's heart is the closest anatomical and physiological match to a human's among affordable large-animal models, making it the standard testbed for cardiac catheters before they reach clinical trials, and increasingly, a transplant organ in its own right.
Skin/Wound Models
Pig skin is the closest animal model to human skin in structure and healing properties. Our skin/wound models are used for wound dressing evaluation, cold plasma treatment equipment testing, skin toxicity testing, and transdermal drug delivery research.
Experiment Types
- Transdermal drug delivery system testing
- Drug skin toxicity and local irritation testing
- Lipolysis reaction and immune response assessment
- Negative pressure wound therapy dressing evaluation
- Skin flap model and tissue transplantation research
- Stem cell dressing wound healing feasibility testing
- Medical cold plasma skin treatment equipment evaluation
Associated Clients
- SGH Biotech Co., Ltd.
- Glonova Pharma Co., Ltd.
- National Taiwan University
- ANNJI Pharmaceutical Co., Ltd.
- China Medical University Hospital
Metabolic / Endocrine Models
Streptozotocin-induced type 1 diabetes is established in pigs within days and holds stable for months under insulin control, giving devices and therapies that need long-term follow-up a sufficient observation window. Porcine skin resembles human skin in epidermal and dermal thickness and in adnexal distribution, and — like human skin, and unlike rodent skin — lacks the panniculus carnosus: rodent wounds close largely by contraction, whereas porcine and human wounds heal by re-epithelialisation and granulation tissue. Diabetic wound-healing results therefore translate more directly. A single animal accommodates several test wounds and sensor sites at once, which suits accuracy and wear-duration validation for continuous glucose monitoring (CGM).
Experiment Types
- Type 1 diabetes model induction and glucose monitoring
- Continuous glucose monitoring (CGM) accuracy validation
- Diabetic wound healing assessment
Associated Clients
- TaiDoc Technology Corp.
Beyond the models
These are not disease models, but they are part of what we take on.
Veterinary and medical training
We also host veterinary and medical training programmes. Surgeons complete hands-on practice on pigs before performing a new procedure for the first time, which supports subsequent TFDA approval and reduces the risk of that first clinical use.
Associated Clients
- Kouken International Education Co., Ltd.
Custom study design and cross-disciplinary matching
Drawing on extensive cross-disciplinary collaboration experience, we identify the most suitable animal models for each client, design customized experimental protocols, and connect clients with the right partners. We help clients meet FDA, CE, and other regulatory standards, completing pre-clinical proof-of-concept, safety, and efficacy evaluations to accelerate the path to market.
- Imaging equipment animal validation
- Customized experimental design
Associated Clients
- Industrial Technology Research Institute
- National Health Research Institutes